Industry 4.0—also called the Fourth Industrial Revolution or 4IR—is the next phase in the digitization of the manufacturing sector. The current era of connectivity, advanced analytics, automation, and advanced-manufacturing technology is transforming global manufacturing business. The intelligent computers—are shaping the Fourth Industrial Revolution. Key Enablers of the 4IR are: 1. Connectivity, data, and computational power: cloud technology, the Internet, blockchain, sensors 2. Analytics and intelligence: advanced analytics, machine learning, artificial intelligence 3. Human–machine interaction: virtual reality (VR) and augmented reality (AR), robotics and automation 4. Advanced Engineering: Additive manufacturing (eg, 3-D printing), Nanoparticles